Kissimmee is the largest city and county seat of Osceola County, Florida, United States. As of the 2020 census, the population was 79,226. It is a Principal City of the Orlando-Kissimmee-Sanford, Florida, Metropolitan Statistical Area, which had a 2010 population of 2,234,411.

Kissimmee features a multi-modal transportation hub located between Neptune Road and Monument Streets. This hub includes the Amtrak train station, which is a station stop on the SunRail commuter rail system. There is a Greyhound bus station. The hub also features a bus terminal providing service by the Lynx network.

Kissimmee Gateway Airport has four fixed-base operators that provide service to the area. Kissimmee Gateway Airport (ISM) accommodates general aviation air service 24 hours a day with two paved airport runways—respectively 5,000 and 6,000 feet. There are also two flight training schools and a museum at the airport. Orlando International Airport can be reached from Kissimmee in 15 minutes by car.

The major roads in the Kissimmee area are Florida's Turnpike, Interstate 4, Osceola Parkway, and US 192. Among other important routes are US 17/92 that join with US 441 into the Orange Blossom Trail (OBT) and the John Young Parkway.